The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Cornichon homolog 2
Cornichon homolog 2 (Drosophila)
Cornichon like protein
Cornichon, Drosophila, homolog of, 2
Protein cornichon homolog 2
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors.
Belongs to the cornichon family.
Endoplasmic reticulum membrane. Cell junction > synapse > postsynaptic cell membrane. Cell projection > dendrite. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).