Recombinant Human PRUNE protein (ab153466)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
Description
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Product name
Recombinant Human PRUNE protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MEDYLQGCRAALQESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEE VFVPVLNIKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQL TLILVDHHILSKSDTALEEAVAEVLDHRPIEPKHCPPCHVSVELVGSCAT LVTERILQGAPEILDRQTAALLHGTIILDCVNMDLKIGKATPKDSKYVEK LEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGVKVAI SAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLA IFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKK LLPLLQEALSAYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQ DEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASL SKK -
Amino acids
1 to 453 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab153466 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- DRES-17
- DRES17
- Drosophila-related expressed sequence 17
see all -
Function
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. -
Tissue specificity
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas. -
Sequence similarities
Belongs to the PPase class C family. Prune subfamily. -
Cellular localization
Cytoplasm. Nucleus. Cell junction > focal adhesion. In some transfected cells a nuclear staining is also observed. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab153466 has not yet been referenced specifically in any publications.