Recombinant Human PSCA protein (ab159927)

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SDS-PAGE - Recombinant Human PSCA protein (ab159927)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human PSCA protein
      See all PSCA proteins and peptides

    • Expression system

      Wheat germ

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        CYSCKAQVSNEDCLQVENCTQLGEQCWTARIRAVGLLTVISKGCSLNCVD DSQDYYVGKKNITCCDTDLCNAS

      • Amino acids

        23 to 95

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab159927 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • PRO 232
      • PRO232
      • Prostate stem cell antigen

    • Relevance

      PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

    • Cellular localization

      Cell membrane; Lipid-anchor, GPI-anchor.

    Images

    • SDS-PAGE - Recombinant Human PSCA protein (ab159927)
      SDS-PAGE - Recombinant Human PSCA protein (ab159927)
      ab159927 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (1)

    Publishing research using ab159927? Please let us know so that we can cite the reference in this datasheet.

    ab159927 has been referenced in 1 publication.

    • Liu N  et al. Simultaneous and combined detection of multiple tumor biomarkers for prostate cancer in human serum by suspension array technology. Biosens Bioelectron 47:92-8 (2013). PubMed: 23567627

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