Recombinant Human PSMB4 protein (ab115721)

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Overview

  • Product name
    Recombinant Human PSMB4 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      P28070
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMTQNPMVTGTSVLGVKFEGGVVIAADMLGS YGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGD GHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLG VAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYR DARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGFE
    • Molecular weight
      27 kDa including tags
    • Amino acids
      46 to 264
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab115721 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab115721 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Additional notes

     This product was previously labelled as Proteasome subunit beta type 4

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 30% Glycerol, 0.02% DTT, 0.58% Sodium chloride

General Info

  • Alternative names
    • 26 kDa prosomal protein
    • HN3
    • HsBPROS26
    • HSN3
    • Macropain beta chain
    • Multicatalytic endopeptidase complex beta chain
    • PROS-26
    • PROS26
    • Proteasome (prosome macropain) subunit beta type 4
    • Proteasome beta 4 subunit
    • Proteasome beta chain
    • Proteasome chain 3
    • Proteasome subunit beta 4
    • Proteasome subunit beta type 4
    • Proteasome subunit beta type-4
    • Proteasome subunit HsN3
    • PSB4_HUMAN
    • PSMB 4
    • PSMB4
    see all
  • Function
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
  • Sequence similarities
    Belongs to the peptidase T1B family.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human PSMB4 protein (ab115721)
    SDS-PAGE - Recombinant Human PSMB4 protein (ab115721)
    15% SDS-PAGE showing ab115721 at approximately 26.6kDa (3µg).

References

ab115721 has not yet been referenced specifically in any publications.

Publishing research using ab115721? Please let us know so that we can cite the reference in this datasheet.

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