Recombinant Human PSMB4 protein (ab115721)

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SDS-PAGE - Recombinant Human PSMB4 protein (ab115721)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: MS, SDS-PAGE

    Description

    • Product name

      Recombinant Human PSMB4 protein

    • Purity

      > 90 % SDS-PAGE.
      ab115721 was purified using conventional chromatography techniques.

    • Expression system

      Escherichia coli

    • Accession

      P28070

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSSHHHHHHSSGLVPRGSHMTQNPMVTGTSVLGVKFEGGVVIAADMLGS YGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGD GHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLG VAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYR DARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGFE

      • Predicted molecular weight

        27 kDa including tags

      • Amino acids

        46 to 264

      • Tags

        His tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab115721 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Mass Spectrometry

      SDS-PAGE

    • Mass spectrometry

      MALDI-TOF

    • Form

      Liquid

    • Additional notes

       This product was previously labelled as Proteasome subunit beta type 4

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.02% DTT, 0.32% Tris HCl, 30% Glycerol (glycerin, glycerine), 0.58% Sodium chloride

    General Info

    • Alternative names

      • 26 kDa prosomal protein
      • HN3
      • HsBPROS26
      • HSN3
      • Macropain beta chain
      • Multicatalytic endopeptidase complex beta chain
      • PROS-26
      • PROS26
      • Proteasome (prosome macropain) subunit beta type 4
      • Proteasome beta 4 subunit
      • Proteasome beta chain
      • Proteasome chain 3
      • Proteasome subunit beta 4
      • Proteasome subunit beta type 4
      • Proteasome subunit beta type-4
      • Proteasome subunit HsN3
      • PSB4_HUMAN
      • PSMB 4
      • PSMB4
      see all

    • Function

      The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

    • Sequence similarities

      Belongs to the peptidase T1B family.

    • Cellular localization

      Cytoplasm. Nucleus.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human PSMB4 protein (ab115721)
      SDS-PAGE - Recombinant Human PSMB4 protein (ab115721)
      15% SDS-PAGE showing ab115721 at approximately 26.6kDa (3µg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab115721? Please let us know so that we can cite the reference in this datasheet.

    ab115721 has not yet been referenced specifically in any publications.

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