Description

  • Product name

    Recombinant Human PSMD11 protein (denatured)
    See all PSMD11 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSHMAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDE EAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVR SLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDT KRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAAL TSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYD SIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCV AQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIE PFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDE PPVDKTYEAALETIQNMSKVVDSLYNKAKKLT
    • Predicted molecular weight

      50 kDa including tags
    • Amino acids

      1 to 422
    • Tags

      His tag N-Terminus
  • Description

    Recombinant Human PSMD11 protein

Specifications

Our Abpromise guarantee covers the use of ab174394 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names

    • 26S proteasome non-ATPase regulatory subunit 11
    • 26S proteasome regulatory subunit 9
    • 26S proteasome regulatory subunit p44.5
    • 26S proteasome regulatory subunit RPN6
    • 26S proteasome regulatory subunit S9
    • MGC3844
    • p44.5
    • protease 26S, subunit, 9
    • proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
    • proteasome 26S subunit, non-ATPase, 11
    • PSD11_HUMAN
    • PSMD 11
    • PSMD11
    • Rpn6
    • S9
    see all
  • Function

    Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
  • Tissue specificity

    Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.
  • Sequence similarities

    Belongs to the proteasome subunit S9 family.
    Contains 1 PCI domain.
  • Post-translational
    modifications

    Phosphorylated by AMPK.
  • Cellular localization

    Nucleus. Cytoplasm > cytosol.
  • Information by UniProt

Images

  • SDS-PAGE analysis of PSMD11 using 3 µg of ab174394 on a 15% gel.

References

ab174394 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab174394.
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