Overview

  • Product name

    Recombinant Human PTGR1 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSEFMVRTK TWTLKKHFVG YPTNSDFELK TAELPPLKNG EVLLEALFLT VDPYMRVAAK RLKEGDTMMG QQVAKVVESK NVALPKGTIV LASPGWTTHS ISDGKDLEKL LTEWPDTIPL SLALGTVGMP GLTAYFGLLE ICGVKGGETV MVNAAAGAVG SVVGQIAKLK GCKVVGAVGS DEKVAYLQKL GFDVVFNYKT VESLEETLKK ASPDGYDCYF DNVGGEFSNT VIGQMKKFGR IAICGAISTY NRTGPLPPGP PPEIVIYQEL RMEAFVVYRW QGDARQKALK DLLKWVLEGK IQYKEYIIEG FENMPAAFMG MLKGDNLGKT IVKA
    • Molecular weight

      39 kDa including tags
    • Amino acids

      1 to 329
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab130018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 90 % SDS-PAGE.
    ab130018 was purified using conventional chromatography techniques.
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names

    • 15-oxoprostaglandin 13-reductase
    • FLJ99229
    • leukotriene B4 12-hydroxydehydrogenase
    • LTB4DH
    • MGC34943
    • NADP-dependent leukotriene B4 12-hydroxydehydrogenase
    • PGR1
    • PRG-1
    • Prostaglandin reductase 1
    • Ptgr1
    • PTGR1_HUMAN
    • RP11-16L21.1
    • ZADH3
    • zinc binding alcohol dehydrogenase domain containing 3
    see all
  • Function

    Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
  • Tissue specificity

    High expression in the kidney, liver, and intestine but not in leukocytes.
  • Sequence similarities

    Belongs to the NADP-dependent oxidoreductase L4BD family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab130018 (3 µg).

References

ab130018 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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