Recombinant human PTPRS protein (ab90018)
Key features and details
- Expression system: Escherichia coli
- Purity: > 70% SDS-PAGE
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
Description
-
Product name
Recombinant human PTPRS protein
See all PTPRS proteins and peptides -
Biological activity
Specific Activity: 223.2 pmol/min/mg. The specific activity of PTPRS was determined using pNPP. Enzyme reaction condition: 20 mM pNPP, 2 min incubation at 30°C, 1 ug enzyme. Assay buffer: 50 mM HEPES, pH 7.4, 2 mM EDTA, 3 mM DTT, 100 mM NaCl,50 mM pNPP.
-
Purity
> 70 % SDS-PAGE. -
Expression system
Escherichia coli -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Predicted molecular weight
98 kDa including tags -
Amino acids
883 to 1501 -
Tags
GST tag N-Terminus -
Additional sequence information
GenBank Accession No. BC104812
-
Specifications
Our Abpromise guarantee covers the use of ab90018 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Functional Studies
SDS-PAGE
-
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on Dry Ice. Store at -80°C.
pH: 8.00
Constituents: 0.0462% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.395% Tris HCl, 0.05% Tween, 20% Glycerol (glycerin, glycerine), 0.58% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
-
Alternative names
- Protein tyrosine phosphatase PTPsigma
- Protein tyrosine phosphatase receptor type S
- Protein tyrosine phosphatase receptor type sigma
see all -
Function
Interacts with LAR-interacting protein LIP.1. -
Tissue specificity
Detected in all tissues tested except for placenta and liver. -
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Contains 8 fibronectin type-III domains.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 tyrosine-protein phosphatase domains. -
Post-translational
modificationsA cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization. -
Cellular localization
Membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab90018 has not yet been referenced specifically in any publications.