Description

  • Product name

    Recombinant Human RAET1E protein (His tag)
    See all RAET1E proteins and peptides
  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Baculovirus infected insect cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      ADPHSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLL GKKVYATSTWGELTQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQ REAERCTGASWQFATNGEKSLLFDAMNMTWTVINHEASKIKETWKKDRGL EKYFRKLSKGDCDHWLREFLGHWEAMPEPTVSPVNASDIHWSSSSLPDHH HHHH
    • Predicted molecular weight

      23 kDa including tags
    • Amino acids

      31 to 225
    • Tags

      His tag C-Terminus
    • Additional sequence information

      NP_631904. Product corresponds to the extracellular domain of ULBP4.

Specifications

Our Abpromise guarantee covers the use of ab227409 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

     This product was previously labelled as ULBP4

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituents: PBS, 10% Glycerol

General Info

  • Alternative names

    • bA350J20.7
    • LETAL
    • Lymphocyte effector toxicity activation ligand
    • MGC125308
    • MGC125309
    • N2DL-4
    • N2DL4
    • N2DL4_HUMAN
    • NKG2D ligand 4
    • NKG2D ligand 4 precursor
    • NKG2DL4
    • RAE-1-like transcript 4
    • RAET1E
    • RAET1E2
    • Retinoic acid early transcript 1E
    • RL-4
    see all
  • Function

    Ligand for the NKG2D receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes.
  • Tissue specificity

    Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid.
  • Sequence similarities

    Belongs to the MHC class I family.
  • Cellular localization

    Secreted and Membrane.
  • Information by UniProt

Images

  • ab227409 (3 μg) analysed by 15% SDS-PAGE.

References

ab227409 has not yet been referenced specifically in any publications.

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