Recombinant Human RARS2 protein (ab163465)

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Description

  • Product name

    Recombinant Human RARS2 protein

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MACGFRRAIACQLSRVLNLPPENLITSISAVPISQKEEVADFQLSVDSLL EKDNDHSRPDIQVQAKRLAEKLRCDTVVSEISTGQRTVNFKINRELLTKT VLQQVIEDGSKYGLKSELFSGLPQKKIVVEFSSPNVAKKFHVGHLRSTII GNFIANLKEALGHQVIRINYLGDWGMQFGLLGTGFQLFGYEEKLQSNPLQ HLFEVYVQVNKEAADDKSVAKAAQEFFQRLELGDVQALSLWQKFRDLSIE EYIRVYKRLGVYFDEYSGESFYREKSQEVLKLLESKGLLLRTIKGTAVVD LSGNGDPSSICTVMRSDGTSLYATRDLAAAIDRMDKYNFDTMIYVTDKGQ KKHFQQVFQMLKIMGYDWAERCQHVPFGVVQGMKTRRGDVTFLEDVLNEI QLRMLQNMASIKTTKELKNPQETAERVGLAALIIQDFKGLLLSDYKFSWD RVFQSRGDTGVFLQYTHARLHSLEETFGCGYLNDFNTACLQEPQSVSILQ HLLRFDEVLYKSSQDFQPRHIVSYLLTLSHLAAVAHKTLQIKDSPPEVAG ARLHLFKAVRSVLANGMKLLGITPVCRM

    • Amino acids

      1 to 578

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab163465 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • arginine tRNA ligase
    • Arginyl tRNA synthetase
    • arginyl tRNA synthetase 2 mitochondrial
    • Arginyl-tRNA synthetase
    • ArgRS
    • DALRD2
    • mitochondrial
    • PCH6
    • Probable arginine tRNA ligase
    • probable arginine tRNA ligase mitochondrial
    • Probable arginine--tRNA ligase
    • probable arginyl tRNA synthetase mitochondrial
    • RARS2
    • RARSL
    • SYRM_HUMAN
    see all

  • Involvement in disease

    Defects in RARS2 are the cause of pontocerebellar hypoplasia type 6 (PCH6) [MIM:611523]; also known as fatal infantile encephalopathy with mitochondrial respiratory chain defects. Pontocerebellar hypoplasia (PCH) is a heterogeneous group of disorders characterized by an abnormally small cerebellum and brainstem.

  • Sequence similarities

    Belongs to the class-I aminoacyl-tRNA synthetase family.

  • Cellular localization

    Mitochondrion matrix.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human RARS2 protein (ab163465)
    SDS-PAGE - Recombinant Human RARS2 protein (ab163465)
    ab163465 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab163465 has not yet been referenced specifically in any publications.

Publishing research using ab163465? Please let us know so that we can cite the reference in this datasheet.

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