Description

  • Product name

    Recombinant Human RBP4 protein
    See all RBP4 proteins and peptides
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMK YWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSE RNLL
    • Amino acids

      19 to 201

Specifications

Our Abpromise guarantee covers the use of ab59967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Endotoxin test showed more than 0.5 EU/mg endotoxin level.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: PBS, 0.02025% Potassium chloride, 0.7946% Sodium chloride

General Info

  • Alternative names

    • OTTHUMP00000020114
    • OTTHUMP00000020115
    • OTTHUMP00000020116
    • Plasma retinol binding protein 4
    • Plasma retinol-binding protein
    • Plasma retinol-binding protein(1-176)
    • PRBP
    • PRO2222
    • RBP
    • RBP4
    • RDCCAS
    • RET4_HUMAN
    • Retinol binding protein 4
    • Retinol binding protein 4 interstitial
    • Retinol binding protein 4 plasma
    see all
  • Function

    Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
  • Involvement in disease

    Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
  • Sequence similarities

    Belongs to the calycin superfamily. Lipocalin family.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • ab59967 on 15% SDS-PAGE (3µg).
  • Anti-RBP4 antibody (ab73022) at 1 µg/ml + Recombinant Human RBP4 protein (ab59967) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Exposure time: 90 seconds

References

This product has been referenced in:

  • Paul A  et al. Picomolar detection of retinol binding protein 4 for early management of type II diabetes. Biosens Bioelectron 128:122-128 (2019). Read more (PubMed: 30641454) »
See 1 Publication for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Question
Answer

Thank you for your enquiry. This product contains protein in PBS buffer (10mM NaH2PO4, 137mM NaCl, 2.7mM KCl, pH7.4) and doesn’t include any other components such as BSA, sodium azide etc. However, as the result of endotoxin test this product showed more than 0.5 EU/mg endotoxin level. I hope this information will be useful.

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Question
Answer

Thank you for your enquiry. I can confirm that this product is sodium azide free. Furthermore, the buffer-composition of this product is 10mM Phosphate, 137mM NaCl, 2.7mM KCl, pH7.4 (PBS,pH7.4) and this product has no other constituent.

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