Description

  • Product name

    Recombinant Human RCAS1 protein
  • Purity

    > 90 % SDS-PAGE.
    ab79243 is purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MRSGRGRKLS GDQITLPTTV DYSSVPKQTD VEEWTSWDED APTSVKIEGG NGNVATQQNS LEQLEPDYFK DMTPTIRKTQ KIVIKKREPL NFGIPDGSTG FSSRLAATQD LPFIHQSSEL GDLDTWQENT NAWEEEEDAA WQAEEVLRQQ KLADREKRAA EQQRKKMEKE AQRLMKKEQN KIGVKLS

Specifications

Our Abpromise guarantee covers the use of ab79243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.0154% DTT, 0.242% Tris, 0.0584% EDTA, 10% Glycerol

General Info

  • Alternative names

    • BAG9
    • Cancer associated surface antigen
    • Cancer associated surface antigen RCAS1
    • Cancer-associated surface antigen RCAS1
    • EB9
    • EBAG 9
    • EBAG9
    • Estrogen receptor binding fragment associated gene 9 protein
    • Estrogen receptor binding site associated antigen 9
    • estrogen receptor binding site associated, antigen, 9
    • Estrogen receptor-binding fragment-associated gene 9 protein
    • PDAF
    • RCAS 1
    • RCAS1
    • RCAS1_HUMAN
    • Receptor binding cancer antigen expressed on SiSo cells
    • Receptor-binding cancer antigen expressed on SiSo cells
    see all
  • Function

    May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
  • Tissue specificity

    Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs.
  • Domain

    The coiled coil domain is necessary for the homodimerization.
  • Cellular localization

    Golgi apparatus membrane. According to PubMed:10426319, it also exists as a soluble form which has the same biological activities. The existence of such soluble form is however uncertain.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab79243 (3µg).
    Note: Real molecular weight on SDS-PAGE is shifted up compared to predicted molecular weight.

References

ab79243 has not yet been referenced specifically in any publications.

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