Name: Recombinant Human RDH11 protein
SKU: ab162417

Product name

Recombinant Human RDH11 protein
Protein length

Full length protein

Nature

Recombinant
Source

Wheat germ
Amino Acid Sequence
- Species
  
  Human
- Sequence
  
  IRKMLSSGVCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACR DVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHV LINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIV NVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELARRLKGS GVTTYSVHPGTVQSELVRHSSFMRWMWWLFSFFIKTPQQGAQTSLHCALT EGLEILSGNHFSDCHVAWVSAQARNETIARRLWDVSCDLLGLPID
- Amino acids
  
  24 to 318
- Tags
  
  proprietary tag N-Terminus

Our Abpromise guarantee covers the use of ab162417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

Western blot

ELISA
Form

Liquid
Additional notes

Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...

Stability and Storage

Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl

Alternative names
- Androgen regulated short chain dehydrogenase/reductase 1
- Androgen-regulated short-chain dehydrogenase/reductase 1
- ARSDR1
- AU045252
- C85936
- CGI 82
- FLJ32633
- HCBP12
- HCV core binding protein
- HCV core binding protein HCBP12
- HCV core-binding protein HCBP12
- MDT1
- Prostate short chain dehydrogenase/reductase 1
- Prostate short-chain dehydrogenase/reductase 1
- PSDR1
- RALR1
- RDH11
- RDH11_HUMAN
- Retinal reductase 1
- Retinol dehydrogenase 11
- retinol dehydrogenase 11 (all trans/9 cis/11 cis)
- SCALD
- SDR7C1
- Short chain dehydrogenase/reductase family 7C, member 1
see all
Function

Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.
Tissue specificity

Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.
Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Post-translational
modifications

Not glycosylated.
Cellular localization

Endoplasmic reticulum membrane.
Target information above from: UniProt accession Q8TC12 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human RDH11 protein (ab162417)

ab162417 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Datasheet

ab162417 has not yet been referenced specifically in any publications.

Publishing research using ab162417? Please let us know so that we can cite the reference in this datasheet.

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Recombinant Human RDH11 protein (ab162417)

Overview

Description

Specifications

Preparation and Storage

General Info

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References

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