Recombinant Human RDH11 protein (ab162417)
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- References
- Protocols
Description
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Product name
Recombinant Human RDH11 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
IRKMLSSGVCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACR DVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHV LINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIV NVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELARRLKGS GVTTYSVHPGTVQSELVRHSSFMRWMWWLFSFFIKTPQQGAQTSLHCALT EGLEILSGNHFSDCHVAWVSAQARNETIARRLWDVSCDLLGLPID -
Amino acids
24 to 318 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab162417 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
Protein concentration is above or equal to 0.05 mg/ml. -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- Androgen regulated short chain dehydrogenase/reductase 1
- Androgen-regulated short-chain dehydrogenase/reductase 1
- ARSDR1
see all -
Function
Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. -
Tissue specificity
Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes. -
Sequence similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family. -
Post-translational
modificationsNot glycosylated. -
Cellular localization
Endoplasmic reticulum membrane. - Information by UniProt
Images
Datasheets and documents
References
ab162417 has not yet been referenced specifically in any publications.