Recombinant Human RDH11 protein (ab162417)

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Description

  • Product name

    Recombinant Human RDH11 protein

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      IRKMLSSGVCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACR DVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHV LINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIV NVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELARRLKGS GVTTYSVHPGTVQSELVRHSSFMRWMWWLFSFFIKTPQQGAQTSLHCALT EGLEILSGNHFSDCHVAWVSAQARNETIARRLWDVSCDLLGLPID

    • Amino acids

      24 to 318

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Androgen regulated short chain dehydrogenase/reductase 1
    • Androgen-regulated short-chain dehydrogenase/reductase 1
    • ARSDR1
    • AU045252
    • C85936
    • CGI 82
    • FLJ32633
    • HCBP12
    • HCV core binding protein
    • HCV core binding protein HCBP12
    • HCV core-binding protein HCBP12
    • MDT1
    • Prostate short chain dehydrogenase/reductase 1
    • Prostate short-chain dehydrogenase/reductase 1
    • PSDR1
    • RALR1
    • RDH11
    • RDH11_HUMAN
    • Retinal reductase 1
    • Retinol dehydrogenase 11
    • retinol dehydrogenase 11 (all trans/9 cis/11 cis)
    • SCALD
    • SDR7C1
    • Short chain dehydrogenase/reductase family 7C, member 1
    see all

  • Function

    Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.

  • Tissue specificity

    Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.

  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.

  • Post-translational
    modifications

    Not glycosylated.

  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human RDH11 protein (ab162417)
    SDS-PAGE - Recombinant Human RDH11 protein (ab162417)
    ab162417 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162417 has not yet been referenced specifically in any publications.

Publishing research using ab162417? Please let us know so that we can cite the reference in this datasheet.

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