Description

  • Product name

    Recombinant Human RDHE2 protein
  • Purity

    > 90 % SDS-PAGE.
    ab140552 is purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSPKPRKNV AGEIVLITGA GSGLGRLLAL QFARLGSVLV LWDINKEGNE ETCKMAREAG ATRVHAYTCD CSQKEGVYRV ADQVKKEVGD VSILINNAGI VTGKKFLDCP DELMEKSFDV NFKAHLWTYK AFLPAMIAND HGHLVCISSS AGLSGVNGLA DYCASKFAAF GFAESVFVET FVQKQKGIKT TIVCPFFIKT GMFEGCTTGC PSLLPILEPK YAVEKIVEAI LQEKMYLYMP K
    • Predicted molecular weight

      28 kDa including tags
    • Amino acids

      32 to 269
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • EPHD 2
    • EPHD-2
    • EPHD2
    • Epidermal retinal dehydrogenase 2
    • Epidermal retinol dehydrogenase 2
    • FLJ33105
    • RDH E2
    • RDH#2
    • RDH-E2
    • RDHE2_HUMAN
    • Retinal short chain dehydrogenase reductase
    • Retinal short chain dehydrogenase reductase 2
    • Retinal short-chain dehydrogenase reductase 2
    • retSDR2
    • Sdr16c5
    • Short chain dehydrogenase/reductase family 16C member 5
    • Short-chain dehydrogenase/reductase family 16C member 5
    see all
  • Function

    Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans-retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD+/NADH or NADP+/NADPH.
  • Tissue specificity

    Detected in adult lung. Detected at low levels in adult brain, heart, testis, placenta, cervix, pancreas, uterus, stomach, rectum, small intestine, colon, esophagus, thymus, skin, and skin keratinocyte. Expression is higher in psoriasis lesions relative to unaffected skin from psoriasis patients. Detected in fetal kidney, skin and lung.
  • Pathway

    Cofactor metabolism; retinol metabolism.
  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab140552 (3µg).

References

ab140552 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140552.
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