Description

  • Product name

    Recombinant Human REDD-1/DDIT4 protein
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Amino acids

      1 to 232

Specifications

Our Abpromise guarantee covers the use of ab40031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Inhibition Assay

    SDS-PAGE

    Western blot

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.905% Tris acetate, 0.0292% EDTA, 20% Glycerol

General Info

  • Alternative names

    • DDIT4
    • DDIT4_HUMAN
    • Dig2
    • DNA damage inducible transcript 4
    • DNA damage inducible transcript 4 protein
    • DNA damage-inducible transcript 4 protein
    • FLJ20500
    • HIF 1 responsive protein RTP801
    • HIF 1 responsive RTP801
    • HIF-1 responsive protein RTP801
    • Protein regulated in development and DNA damage response 1
    • REDD-1
    • REDD1
    • RTP801
    see all
  • Function

    Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death.
  • Tissue specificity

    Broadly expressed, with lowest levels in brain, skeletal muscle and intestine. Up-regulated in substantia nigra neurons from Parkinson disease patients (at protein level).
  • Sequence similarities

    Belongs to the DDIT4 family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE: Analysis of REDD-1/DDIT4 Recombinant Protein

References

ab40031 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab40031.
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