Recombinant Human REG1 alpha protein (ab152035)
- Datasheet
- References
- Protocols
Overview
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Product name
Recombinant Human REG1 alpha protein
See all REG1 alpha proteins and peptides -
Protein length
Full length protein
Description
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Nature
Recombinant -
Source
HEK 293 cells -
Amino Acid Sequence
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Accession
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Species
Human -
Sequence
QEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNL VSVLTQAEGA FVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSV NPGYCVSLTS STGFQKWKDVPCEDKFSFVCKFKNVDHHHHHH -
Molecular weight
17 kDa including tags -
Amino acids
23 to 166 -
Tags
His tag C-Terminus
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab152035 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
HPLC
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Endotoxin level
< 0.100 Eu/µg -
Purity
> 95 % SDS-PAGE.
ab152035 was determined to be >95% pure by SEC-HPLC and reducing SDS-PAGE. -
Form
Lyophilised -
Additional notes
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Please see notes section.
pH: 7.20
Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride -
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
General Info
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Alternative names
- ICRF
- Islet cells regeneration factor
- Islet of Langerhans regenerating protein
see all -
Function
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. -
Tissue specificity
In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients. -
Sequence similarities
Contains 1 C-type lectin domain. -
Developmental stage
High expression levels in fetal and infant brains; much lower in adult brains. -
Post-translational
modificationsThe composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine. -
Cellular localization
Secreted. - Information by UniProt
Datasheets and documents
References
ab152035 has not yet been referenced specifically in any publications.
