Description

  • Product name

    Recombinant Human REG4 protein (denatured)
    See all REG4 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.
    ab202197 was purified by conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MASMTGGQQM GRGSHMDIIM RPSCAPGWFY HKSNCYGYFR KLRNWSDAEL ECQSYGNGAH LASILSLKEA STIAEYISGY QRSQPIWIGL HDPQKRQQWQ WIDGAMYLYR SWSGKSMGGN KHCAEMSSNN NFLTWSSNEC NKRQHFLCKY RP
    • Predicted molecular weight

      18 kDa including tags
    • Amino acids

      23 to 158
    • Tags

      T7 tag N-Terminus
    • Additional sequence information

      This product is for the mature full length protein from aa 23 to 158. The signal peptide is not included. (NP_114433)
  • Description

    Recombinant Human REG4 protein

Specifications

Our Abpromise guarantee covers the use of ab202197 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • Gastrointestinal secretory protein
    • GISP
    • Reg IV
    • REG like protein
    • REG-4
    • REG-like protein
    • Reg4
    • REG4_HUMAN
    • Regenerating gene type IV
    • Regenerating islet derived family member 4
    • Regenerating islet derived protein 4 precursor
    • Regenerating islet-derived protein 4
    • Regenerating islet-derived protein IV
    • REGIV
    • RELP
    see all
  • Function

    May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
  • Tissue specificity

    Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
  • Sequence similarities

    Contains 1 C-type lectin domain.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab202197 (3ug).

References

ab202197 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab202197.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up