Overview

  • Product name

    Recombinant Human Retinoblastoma binding protein 1
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      AEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGL MAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVS KPQKLAR
    • Amino acids

      1033 to 1139
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159315 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • ARID 4A
    • ARID domain containing protein 4A
    • ARID4A
    • AT rich interactive domain 4A
    • AT rich interactive domain containing protein 4A
    • RBBP 1
    • RBBP1
    • RBP 1
    • RBP1
    • RBP1 like
    see all
  • Relevance

    The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
  • Cellular localization

    Nuclear

Images

  • ab159315 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159315 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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