Description

  • Product name

    Recombinant Human Retinoic Acid Receptor gamma protein
    See all Retinoic Acid Receptor gamma proteins and peptides
  • Biological activity

    1 unit equals 1 nanogram of purified protein.
  • Purity

    > 90 % SDS-PAGE.
    ab81922 is purified by a combination of affinity and gel filtration chromatography.
  • Expression system

    Baculovirus
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human

Specifications

Our Abpromise guarantee covers the use of ab81922 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    1 unit equals 1 nanogram of purified protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.75% Potassium chloride, 0.0154% DTT, 0.316% Tris HCl, 0.00584% EDTA, 20% Glycerol

General Info

  • Alternative names

    • NR1B3
    • Nuclear receptor subfamily 1 group B member 3
    • RAR gamma
    • RAR-gamma
    • RARC
    • Rarg
    • RARG_HUMAN
    • Retinoic acid receptor gamma
    • Retinoic acid receptor gamma 2
    • Retinoic acid receptor, gamma
    see all
  • Function

    Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
  • Sequence similarities

    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Domain

    Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt

References

This product has been referenced in:

See 1 Publication for this product

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