Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGVAIYVNGY TDPSAEELRK LMMLHGGQYH VYYSRSKTTH IIATNLPNAK IKELKGEKVI RPEWIVESIK AGRLLSYIPY QLYTKQSSVQ KGLSFNPVCR PEDPLPGPSN IAKQLNNRVN HIVKKIETEN EVKVNGMNSW NEEDENNDFS FVDLEQTSPG RKQNGIPHPR GSTAIFNGHT PSSNGALKTQ DCLVPMVNSV ASRLSPA
    • Molecular weight

      25 kDa including tags
    • Amino acids

      51 to 256
    • Tags

      His tag N-Terminus
    • Additional sequence information

      (NP_057400).

Specifications

Our Abpromise guarantee covers the use of ab180340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 85 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 2.4% Urea, 10% Glycerol

General Info

  • Alternative names

    • AIBP 80
    • AIBP80
    • Alpha integrin binding protein 80
    • Alpha integrin-binding protein 80
    • DNA repair protein REV 1
    • DNA repair protein REV1
    • FLJ21523
    • MGC163283
    • MGC26225
    • REV 1
    • REV 1 (yeast homolog) like
    • REV 1 homolog
    • REV 1 like
    • REV 1 protein
    • REV 1L
    • REV1
    • REV1 (yeast homolog) like
    • REV1 homolog
    • REV1 homolog (S. cerevisiae)
    • REV1 like
    • REV1 like (yeast)
    • Rev1 like terminal deoxycytidyl transferase
    • REV1 protein
    • Rev1-like terminal deoxycytidyl transferase
    • REV1_HUMAN
    • REV1L
    see all
  • Function

    Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the DNA polymerase type-Y family.
    Contains 1 BRCT domain.
    Contains 1 umuC domain.
  • Domain

    The C-terminal domain is necessary for protein interactions.
  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab180340 (3 μg).

References

ab180340 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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