Recombinant Human RGS19 protein (ab101949)
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- References
- Protocols
Overview
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Product nameRecombinant Human RGS19 protein
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Protein lengthFull length protein
Description
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NatureRecombinant
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SourceEscherichia coli
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Amino Acid Sequence
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Accession
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SpeciesHuman
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SequenceMGSSHHHHHHSSGLVPRGSHMPTPHEAEKQITGPEEADRPPSMSSHDTAS PAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPS PEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEA NQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
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Molecular weight27 kDa including tags
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Amino acids1 to 217
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TagsHis tag N-Terminus
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab101949 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Mass Spectrometry
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Mass spectrometryMALDI-TOF
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Purity> 90 % SDS-PAGE.
ab101949 is purified using conventional chromatography techniques. -
FormLiquid
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: None
Constituents: 10% Glycerol, PBS, pH 7.4
General Info
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Alternative names
- G alpha interacting protein
- G protein signalling regulator 19
- G protein, alpha-interacting protein
see all -
FunctionInhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
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Tissue specificityHighest expression in lung. Placenta, liver and heart also express high levels of GAIP.
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Sequence similaritiesContains 1 RGS domain.
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Post-translational
modificationsFatty acylated. Heavily palmitoylated in the cysteine string motif.
Phosphorylated, mainly on serine residues. -
Cellular localizationMembrane.
- Information by UniProt
Images
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SDS-PAGE - Recombinant Human RGS19 protein (ab101949)15% SDS-PAGE analysis of 3µg ab101949.
Datasheets and documents
References
ab101949 has not yet been referenced specifically in any publications.
