Recombinant Human RHEB protein (ab56271)

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SDS-PAGE - Recombinant Human RHEB protein (ab56271)

    Key features and details

    • Expression system: Baculovirus infected Sf9 cells
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human RHEB protein
      See all RHEB proteins and peptides

    • Expression system

      Baculovirus infected Sf9 cells

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Tags

        His tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab56271 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 7.00
      Preservative: 1.02% Imidazole
      Constituents: 0.82% Sodium phosphate, 0.00308% DTT, 25% Glycerol (glycerin, glycerine), 1.74% Sodium chloride

    General Info

    • Alternative names

      • Ras homolog enriched in brain 2, formerly
      • GTP binding protein Rheb
      • GTP-binding protein Rheb
      • MGC111559
      • Ras homolog enriched in brain
      • Ras homolog enriched in brain 2
      • Rheb
      • RHEB 2
      • RHEB_HUMAN
      • RHEB2
      • RHEB2, formerly
      see all

    • Function

      Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.

    • Tissue specificity

      Ubiquitous. Highest levels observed in skeletal and cardiac muscle.

    • Sequence similarities

      Belongs to the small GTPase superfamily. Rheb family.

    • Post-translational
      modifications

      Farnesylation is important for efficiently activating mTORC1-mediated signaling.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human RHEB protein (ab56271)
      SDS-PAGE - Recombinant Human RHEB protein (ab56271)
      ab56271 on SDS-PAGE.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab56271? Please let us know so that we can cite the reference in this datasheet.

    ab56271 has not yet been referenced specifically in any publications.

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