- Datasheet
- Specific References
- Protocols
Overview
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Product nameRecombinant Human RHEB protein
See all RHEB proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceBaculovirus infected Sf9 cells
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Amino Acid Sequence
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SpeciesHuman
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab56271 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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FormLiquid
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: 150mM Imidazole
Constituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 0.2mM DTT, pH 7.0
General Info
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Alternative names
- Ras homolog enriched in brain 2, formerly
- GTP binding protein Rheb
- GTP-binding protein Rheb
see all -
FunctionStimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
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Tissue specificityUbiquitous. Highest levels observed in skeletal and cardiac muscle.
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Sequence similaritiesBelongs to the small GTPase superfamily. Rheb family.
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Post-translational
modificationsFarnesylation is important for efficiently activating mTORC1-mediated signaling. -
Cellular localizationCell membrane.
- Information by UniProt
Images
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SDS-PAGE - RHEB protein (His tag) (ab56271)ab56271 on SDS-PAGE.
References
ab56271 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"