For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Full length protein
Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.00044% GDP, 0.0475% Magnesium chloride, 0.595% HEPES, 50% Glycerol
- Ras homolog enriched in brain 2, formerly
- GTP binding protein Rheb
- GTP-binding protein Rheb
Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
Belongs to the small GTPase superfamily. Rheb family.
Farnesylation is important for efficiently activating mTORC1-mediated signaling.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"