Recombinant human RIP2 protein (ab60879)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant human RIP2 protein
See all RIP2 proteins and peptides -
Expression system
Baculovirus infected Sf9 cells -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Amino acids
1 to 299
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Associated products
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Substrate reagent
Specifications
Our Abpromise guarantee covers the use of ab60879 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Liquid -
Additional notes
ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- CARD 3
- CARD carrying kinase
- CARD containing ICE associated kinase
see all -
Function
Activates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B. -
Tissue specificity
Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node. -
Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Contains 1 CARD domain.
Contains 1 protein kinase domain. -
Post-translational
modificationsAutophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
Ubiquitinated; undergoes 'Lys-63'-linked polyubiquitination catalyzed by ITCH. -
Cellular localization
Cytoplasm. - Information by UniProt
Images
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Functional Studies - Recombinant human RIP2 protein (ab60879)The specific activity of RIP2 (ab60879) was determined to be 20 nmol/min/mg as per activity assay protocol -
SDS-PAGE - Recombinant human RIP2 protein (ab60879)SDS PAGE analysis of ab60879 -
SDS-PAGE - Recombinant human RIP2 protein (ab60879)SDS PAGE analysis of ab60879 -
Functional Studies - Recombinant human RIP2 protein (ab60879)Sample Kinase Activity Plot. -
SDS-PAGE - Recombinant human RIP2 protein (ab60879)ab60879 on SDS-PAGE, MW ~59 kDa.
Datasheets and documents
References
ab60879 has not yet been referenced specifically in any publications.
