Description

  • Product name

    Recombinant human RIPK5 protein
  • Biological activity

    The Specific activity of ab89694 was determined to be 6 nmol/min/mg.
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab89694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Functional Studies

  • Form

    Liquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • DSTYK
    • Dual serine/threonine and tyrosine protein kinase
    • Dusty PK
    • Dusty protein kinase
    • DUSTY_HUMAN
    • HDCMD38P
    • KIAA0472
    • Receptor interacting protein 5
    • Receptor interacting protein kinase 5
    • Receptor interacting serine/threonine protein kinase 5
    • Receptor-interacting serine/threonine-protein kinase 5
    • RIP homologous kinase
    • RIP-homologous kinase
    • RIP5
    • RIPK5
    • SgK496
    • Sugen kinase 496
    see all
  • Function

    May induce both caspase-dependent apoptosis and caspase-independent cell death.
  • Tissue specificity

    Predominantly expressed in skeletal muscle and testis. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE showing ab89694 at approximately 140kDa.
  • Kinase Assay demonstrating specific activity of ab89694.

References

ab89694 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab89694.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up