Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSKPKGMTS SQWFKIQHMQ PSPQACNSAM KNINKHTKRC KDLNTFLHEP FSSVAATCQT PKIACKNGDK NCHQSHGPVS LTMCKLTSGK YPNCRYKEKR QNKSYVVACK PPQKKDSQQF HLVPVHLDRV L
    • Molecular weight

      17 kDa including tags
    • Amino acids

      26 to 156
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab156334 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 90 % SDS-PAGE.
    ab156334 is purified using conventional chromatography techniques.
  • Form

    Liquid
  • Additional notes

    Protein previously labeled as Ribonuclease 7.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • EC 3.1.27.-
    • MGC133220
    • Ribonuclease 7
    • ribonuclease, RNase A family, 7
    • RNAS7_HUMAN
    • RNase 7
    • RNASE7
    • SAP 2
    • SAP-2
    • Skin derived antimicrobial protein 2
    • Skin-derived antimicrobial protein 2
    see all
  • Function

    Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium.
  • Tissue specificity

    Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart.
  • Sequence similarities

    Belongs to the pancreatic ribonuclease family.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab156334 (3µg).

References

ab156334 has not yet been referenced specifically in any publications.

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