Product nameRecombinant Human ROCK2 protein
See all ROCK2 proteins and peptides
Protein lengthProtein fragment
Amino Acid Sequence
SequenceKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLL LLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRP SRQLAPNKPS
Amino acids1279 to 1388
Tagsproprietary tag N-Terminus
Our Abpromise guarantee covers the use of ab160505 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- coiled-coil-containing protein kinase 2
- p164 ROCK 2
FunctionRegulates the assembly of the actin cytoskeleton. Promotes formation of stress fibers and of focal adhesion complexes. Plays a role in smooth muscle contraction.
Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 protein kinase domain.
Contains 1 REM (Hr1) repeat.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationCytoplasm. Cell membrane. Cytoplasmic, and associated with actin microfilaments and the plasma membrane.
- Information by UniProt
This product has been referenced in:
- Bai H et al. Association of moderate aerobic exercise and rho-associated kinase 2 concentration in subjects with dyslipidemia. Arch Med Sci 13:807-812 (2017). Read more (PubMed: 28721148) »
- Liao HC et al. Effects and mechanism of moderate aerobic exercise on impaired fasting glucose improvement. Lipids Health Dis 14:157 (2015). Human . Read more (PubMed: 26630989) »