Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human
    • Amino acids
      983 to 1400

Associated products

Specifications

Our Abpromise guarantee covers the use of ab70541 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific activity was determined to be 81nmol/min/mg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Form
    Liquid
  • Additional notes

    ab204853 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • c met related tyrosine kinase
    • CD136
    • CD136 antigen
    • CDw136
    • Macrophage stimulating 1 receptor
    • Macrophage stimulating 1 receptor (c met related tyrosine kinase)
    • MACROPHAGE STIMULATING PROTEIN RECEPTOR
    • Macrophage stimulating protein receptor alpha chain
    • Macrophage stimulating protein receptor beta chain
    • Macrophage-Stimulating 1 Receptor (MST1R)
    • Macrophage-stimulating protein receptor beta chain
    • MSP receptor
    • Mst1r
    • MST1R variant RON30
    • MST1R variant RON62
    • NPCA3
    • p185 RON
    • p185-Ron
    • Protein-tyrosine kinase 8
    • PTK 8
    • ptk8
    • PTK8 protein tyrosine kinase 8
    • Recepteur d’origine nantais (RON)
    • RON
    • RON protein tyrosine kinase
    • RON variant E2E3
    • RON_HUMAN
    • Soluble RON variant 1
    • Soluble RON variant 2
    • Soluble RON variant 3
    • Soluble RON variant 4
    • Stem cell derived tyrosine kinase
    see all
  • Function
    Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.
  • Tissue specificity
    Keratinocytes and lung.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family.
    Contains 3 IPT/TIG domains.
    Contains 1 protein kinase domain.
    Contains 1 Sema domain.
  • Post-translational
    modifications
    Proteolytic processing yields the two subunits.
    Phosphorylated in response to ligand binding.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant human RON protein (ab70541)
    SDS-PAGE - Recombinant human RON protein (ab70541)
    SDS-PAGE showing ab70541 at approximately 71kDa.
  • Functional Studies - Recombinant human RON protein (ab70541)
    Functional Studies - Recombinant human RON protein (ab70541)
    Kinase Assay demonstrating Specific activity was determined to be 81nmol/min/mg.

References

ab70541 has not yet been referenced specifically in any publications.

Publishing research using ab70541? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Submit a review Submit a question

There are currently no Customer reviews or Questions for ab70541.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up