Recombinant human RON protein (ab70541)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Description
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Product name
Recombinant human RON protein
See all RON proteins and peptides -
Biological activity
Specific activity was determined to be 81nmol/min/mg. -
Expression system
Baculovirus infected Sf9 cells -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Amino acids
983 to 1400
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Associated products
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Substrate reagent
Specifications
Our Abpromise guarantee covers the use of ab70541 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
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Form
Liquid -
Additional notes
ab204853 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- c met related tyrosine kinase
- CD136
- CD136 antigen
see all -
Function
Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity. -
Tissue specificity
Keratinocytes and lung. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Contains 3 IPT/TIG domains.
Contains 1 protein kinase domain.
Contains 1 Sema domain. -
Post-translational
modificationsProteolytic processing yields the two subunits.
Phosphorylated in response to ligand binding. -
Cellular localization
Membrane. - Information by UniProt
Images
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The specific activity of RON (ab70541) was determined to be 93 nmol/min/mg as per activity assay protocol
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SDS PAGE analysis of ab70541
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SDS PAGE analysis of ab70541
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SDS-PAGE showing ab70541 at approximately 71kDa.
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Kinase Assay demonstrating Specific activity was determined to be 81nmol/min/mg.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab70541 has not yet been referenced specifically in any publications.