Description

  • Product name

    Recombinant Human ROX protein
  • Purity

    > 90 % SDS-PAGE.
    ab183233 was purified using conventional chromatography.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL DSVVRLQFKD HIVLTVLPDQ DQSDETQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV
    • Predicted molecular weight

      55 kDa including tags
    • Amino acids

      1 to 465
    • Tags

      His tag N-Terminus
    • Additional sequence information

      AAH14928

Specifications

Our Abpromise guarantee covers the use of ab183233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

     This product was previously labelled as MINA53

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 10% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • 60S ribosomal protein L27a histidine hydroxylase
    • Bifunctional lysine specific demethylase and histidyl hydroxylase MINA
    • FLJ14393
    • Histone lysine demethylase MINA
    • MDIG
    • MINA
    • MINA_HUMAN
    • Mineral dust-induced gene protein
    • MYC induced nuclear antigen
    • Myc induced nuclear antigen 53 kDa
    • MYC-induced nuclear antigen
    • NO52
    • Nucleolar protein 52
    • Ribosomal oxygenase MINA
    • ROX
    see all
  • Function

    Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
  • Tissue specificity

    Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines.
  • Sequence similarities

    Belongs to the MINA53/NO66 family.
    Contains 1 JmjC domain.
  • Cellular localization

    Nucleus. Nucleus > nucleolus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab183233 (3 µg)

References

ab183233 has not yet been referenced specifically in any publications.

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