Description

  • Product name

    Recombinant Human RPS19 protein
  • Purity

    > 95 % SDS-PAGE.
    Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      PGVTVKDVN QQEFVRALAA FLKKSGKLKV PEWVDTVKLA KHKELAPYDE NWFYTRAAST ARHLYLRGGA GVGSMTKIYG GRQRNGVMPS HFSRGSKSVA RRVLQALEGL KMVEKDQDGG RKLTPQGQRD LDRIAGQVAA ANKKH
    • Predicted molecular weight

      16 kDa
    • Amino acids

      2 to 145

Associated products

Specifications

Our Abpromise guarantee covers the use of ab151818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C.

    pH: 7.40
    Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

General Info

  • Alternative names

    • 40S ribosomal protein S19
    • DBA
    • DBA1
    • HGNC:10402
    • Ribosomal protein S19
    • rps19
    • RS19_HUMAN
    • S19
    see all
  • Function

    Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
  • Tissue specificity

    Higher level expression is seen in the colon carcinoma tissue than normal colon tissue.
  • Involvement in disease

    Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1) [MIM:105650]. DBA1 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
  • Sequence similarities

    Belongs to the ribosomal protein S19e family.
  • Cellular localization

    Nucleus. Located more specifically in the nucleoli.
  • Information by UniProt

References

ab151818 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Question
Answer


Ab151818 - RPS19 protein (human) does not have any tag in the protein sequence.

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