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Recombinant Human RPS6KC1 protein
Amino Acid Sequence
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- 52 kDa ribosomal protein S6 kinase
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.
Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 MIT domain.
Contains 2 protein kinase domains.
Contains 1 PX (phox homology) domain.
The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.
Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"