Recombinant Human RRAGB protein (ab160946)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
Description
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Product name
Recombinant Human RRAGB protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MEESDSEKTTEKENLGPRMDPPLGEPEGSLGWVLPNTAMKKKVLLMGKSG SGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQD TFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNS PDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDE TLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHY QCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFT SNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR -
Amino acids
1 to 346 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab160946 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- GTP-binding protein ragB
- Rag B
- RagB
see all -
Function
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. -
Sequence similarities
Belongs to the GTR/RAG GTP-binding protein family. -
Cellular localization
Cytoplasm. Lysosome. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab160946 has not yet been referenced specifically in any publications.