Recombinant Human RRAGB protein (ab160946)

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Description

  • Product name

    Recombinant Human RRAGB protein

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MEESDSEKTTEKENLGPRMDPPLGEPEGSLGWVLPNTAMKKKVLLMGKSG SGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQD TFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNS PDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDE TLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHY QCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFT SNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR

    • Amino acids

      1 to 346

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160946 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • GTP-binding protein ragB
    • Rag B
    • RagB
    • Ras-related GTP-binding protein B
    • RRAGB
    • RRAGB_HUMAN
    see all

  • Function

    Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway.

  • Sequence similarities

    Belongs to the GTR/RAG GTP-binding protein family.

  • Cellular localization

    Cytoplasm. Lysosome.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human RRAGB protein (ab160946)
    SDS-PAGE - Recombinant Human RRAGB protein (ab160946)
    ab160946 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160946 has not yet been referenced specifically in any publications.

Publishing research using ab160946? Please let us know so that we can cite the reference in this datasheet.

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