Recombinant Human RRAGB protein (ab160946)

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SDS-PAGE - Recombinant Human RRAGB protein (ab160946)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human RRAGB protein

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MEESDSEKTTEKENLGPRMDPPLGEPEGSLGWVLPNTAMKKKVLLMGKSG SGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQD TFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNS PDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDE TLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHY QCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFT SNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR

      • Amino acids

        1 to 346

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab160946 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • GTP-binding protein ragB
      • Rag B
      • RagB
      • Ras-related GTP-binding protein B
      • RRAGB
      • RRAGB_HUMAN
      see all

    • Function

      Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway.

    • Sequence similarities

      Belongs to the GTR/RAG GTP-binding protein family.

    • Cellular localization

      Cytoplasm. Lysosome.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human RRAGB protein (ab160946)
      SDS-PAGE - Recombinant Human RRAGB protein (ab160946)
      ab160946 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab160946? Please let us know so that we can cite the reference in this datasheet.

    ab160946 has not yet been referenced specifically in any publications.

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