Name: Recombinant human RSK1 p90 protein
SKU: ab60880

Product name

Recombinant human RSK1 p90 protein
See all RSK1 p90 proteins and peptides
Protein length

Full length protein

Nature

Recombinant
Source

Baculovirus infected Sf9 cells
Amino Acid Sequence
- Species
  
  Human

Related Products
- Anti-RSK1 p90 antibody [E4] (ab32114)
- Anti-RSK1 p90 antibody [Y81] (ab32526)
Substrate reagent
- RPS6 peptide (ab204880)

Our Abpromise guarantee covers the use of ab60880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

SDS-PAGE

Functional Studies
Form

Liquid
Additional notes

ab204880 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity
Concentration information loading...

Stability and Storage

Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

This product is an active protein and may elicit a biological response in vivo, handle with caution.

Alternative names
- 90 kDa ribosomal protein S6 kinase 1
- dJ590P13.1
- dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1
- EC 2.7.11.1
- HU 1
- HU1
- KS6A1_HUMAN
- MAP kinase activated protein kinase 1a
- MAP kinase-activated protein kinase 1a
- MAPK-activated protein kinase 1a
- MAPKAP kinase 1a
- MAPKAPK-1a
- MAPKAPK1A
- MGC79981
- Mitogen-activated protein kinase-activated protein kinase 1A
- OTTHUMP00000004113
- p90 RSK1
- p90-RSK 1
- p90rsk
- p90RSK1
- p90S6K
- pp90RSK1
- Ribosomal protein S6 kinase 90kD 1
- Ribosomal protein S6 kinase 90kD polypeptide 1
- Ribosomal protein S6 kinase 90kDa polypeptide 1
- Ribosomal protein S6 kinase alpha 1
- Ribosomal protein S6 kinase alpha-1
- Ribosomal protein S6 kinase polypeptide 1
- Ribosomal S6 kinase 1
- RPS6K1 alpha
- rps6ka
- Rps6ka1
- RSK
- RSK 1
- RSK 1 p90
- RSK-1
- RSK1
- S6K alpha 1
- S6K-alpha-1
see all
Function

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
Sequence similarities

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 2 protein kinase domains.
Post-translational
modifications

Autophosphorylated on Ser-380, as part of the activation process.
Target information above from: UniProt accession Q15418 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

Functional Studies - Recombinant human RSK1 p90 protein (ab60880)

Sample Kinase Activity Plot.
SDS-PAGE - Recombinant human RSK1 p90 protein (ab60880)

ab60880 on SDS-PAGE, MW ~108 kDa.

Datasheet

This product has been referenced in:

Kroczynska B et al. Regulatory effects of ribosomal S6 kinase 1 (RSK1) in IFN{lambda} signaling. J Biol Chem 286:1147-56 (2011). Read more (PubMed: 21075852) »

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Recombinant human RSK1 p90 protein (ab60880)

Overview

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