Recombinant human RSK1 p90 protein (ab60880)
- Datasheet
- References (1)
- Protocols
Description
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Product name
Recombinant human RSK1 p90 protein
See all RSK1 p90 proteins and peptides -
Expression system
Baculovirus infected Sf9 cells -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human
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Associated products
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Related Products
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Substrate reagent
Specifications
Our Abpromise guarantee covers the use of ab60880 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Liquid -
Additional notes
ab204880 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- 90 kDa ribosomal protein S6 kinase 1
- dJ590P13.1
- dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1
see all -
Function
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. -
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 2 protein kinase domains. -
Post-translational
modificationsAutophosphorylated on Ser-380, as part of the activation process. - Information by UniProt
Images
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Functional Studies - Recombinant human RSK1 p90 protein (ab60880)The specific activity of RSK1 p90 (ab60880) was determined to be 210 nmol/min/mg as per activity assay protocol -
SDS-PAGE - Recombinant human RSK1 p90 protein (ab60880)SDS PAGE analysis of ab60880 -
SDS-PAGE - Recombinant human RSK1 p90 protein (ab60880)SDS PAGE analysis of ab60880 -
Functional Studies - Recombinant human RSK1 p90 protein (ab60880)Sample Kinase Activity Plot. -
SDS-PAGE - Recombinant human RSK1 p90 protein (ab60880)ab60880 on SDS-PAGE, MW ~108 kDa.
Datasheets and documents
References
This product has been referenced in:
- Kroczynska B et al. Regulatory effects of ribosomal S6 kinase 1 (RSK1) in IFN{lambda} signaling. J Biol Chem 286:1147-56 (2011). Read more (PubMed: 21075852) »
