Recombinant Human S100 alpha 6/PRA protein (ab104645)

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Description

  • Product name

    Recombinant Human S100 alpha 6/PRA protein
    See all S100 alpha 6/PRA proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    ab104645 is purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.

  • Expression system

    Escherichia coli

  • Accession

    P06703

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHHSSGLVPRGSHMACPLDQAIGLLVAIFHKYSGREGDKHTLS KKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGAL ALIYNEALKG

    • Predicted molecular weight

      12 kDa including tags

    • Amino acids

      1 to 90

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab104645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid

  • Additional notes

     This product was previously labelled as S100 alpha 6

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.0154% DTT, 0.316% Tris HCl, 30% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names

    • 2A9
    • 5B10
    • CABP
    • CACY
    • Calcyclin
    • Growth factor inducible protein 2A9
    • Growth factor-inducible protein 2A9
    • MLN 4
    • MLN4
    • OTTHUMP00000015472
    • OTTHUMP00000015473
    • PRA
    • PRAGrowth factor inducible protein 2A9
    • Prolactin receptor associated protein
    • Prolactin receptor-associated protein
    • Protein S100 A6
    • Protein S100-A6
    • S100 A6
    • S100 calcium binding protein A6
    • S100 calcium binding protein A6 (calcyclin)
    • S100 calcium-binding protein A6
    • S100A6
    • S10A6_HUMAN
    see all

  • Function

    May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.

  • Sequence similarities

    Belongs to the S-100 family.
    Contains 2 EF-hand domains.

  • Post-translational
    modifications

    The N-terminus is blocked.

  • Cellular localization

    Nucleus envelope. Cytoplasm. Cell membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human S100 alpha 6/PRA protein (ab104645)
    SDS-PAGE - Recombinant Human S100 alpha 6/PRA protein (ab104645)
    15% SDS-PAGE showing ab104645 at approximately 12.3kDa (3µg).

References

This product has been referenced in:

  • Lorenzi R  et al. Soluble form of receptor for advanced glycation end-products (sRAGE): do sRAGE ligands or anti-sRAGE auto-antibodies interfere with sRAGE quantification? Ann Clin Biochem N/A:N/A (2013). Read more (PubMed: 23982266) »
See 1 Publication for this product

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