Recombinant Human S100 beta protein (ab55570)

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SDS-PAGE - Recombinant Human S100 beta protein (ab55570)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human S100 beta protein
      See all S100 beta proteins and peptides

    • Purity

      > 95 % SDS-PAGE.

    • Expression system

      Escherichia coli

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Amino Acid Sequence 1

      • Species

        Human

      • Sequence

        SELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQ EVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE

      • Amino acids

        2 to 92

      • Amino Acid Sequence 2

      • Species

        Human

      • Sequence

        SELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQ EVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE

      • Amino acids

        2 to 92

    Specifications

    Our Abpromise guarantee covers the use of ab55570 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

      Constituent: 50% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • NEF
      • Protein S100 B
      • Protein S100-B
      • S 100 calcium binding protein beta chain
      • S 100 protein beta chain
      • S-100 protein beta chain
      • S-100 protein subunit beta
      • S100
      • S100 calcium binding protein beta (neural)
      • S100 calcium-binding protein B
      • S100 protein beta chain
      • S100B
      • S100B_HUMAN
      • S100beta
      see all

    • Function

      Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.

    • Tissue specificity

      Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

    • Sequence similarities

      Belongs to the S-101 family.
      Contains 2 EF-hand domains.

    • Cellular localization

      Cytoplasm. Nucleus.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human S100 beta protein (ab55570)
      SDS-PAGE - Recombinant Human S100 beta protein (ab55570)
      ab55570 on SDS-PAGE

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab55570? Please let us know so that we can cite the reference in this datasheet.

    ab55570 has not yet been referenced specifically in any publications.

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