Name: Recombinant Human S100 beta protein
SKU: ab55570

Product name

Recombinant Human S100 beta protein
See all S100 beta proteins and peptides
Protein length

Full length protein

Our Abpromise guarantee covers the use of ab55570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Alternative names
- NEF
- Protein S100 B
- Protein S100-B
- S 100 calcium binding protein beta chain
- S 100 protein beta chain
- S-100 protein beta chain
- S-100 protein subunit beta
- S100
- S100 calcium binding protein beta (neural)
- S100 calcium-binding protein B
- S100 protein beta chain
- S100B
- S100B_HUMAN
- S100beta
see all
Function

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Tissue specificity

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
Sequence similarities

Belongs to the S-101 family.
Contains 2 EF-hand domains.
Cellular localization

Cytoplasm. Nucleus.
Target information above from: UniProt accession P04271 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

ab55570 has not yet been referenced specifically in any publications.

Publishing research using ab55570? Please let us know so that we can cite the reference in this datasheet.

Recombinant Human S100 beta protein (ab55570)

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