Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      NRGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICINASNWQDKSMG CENGHVPLYSSSSVPTTINTIGTSTSTILSGQAHHSPLKRSVSLTPPMNV PNQPLGHGWM
    • Amino acids

      161 to 270
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • KIAA1053
    • protein Smaug homolog 1
    • SAM domain-containing protein 4A
    • SAMD4
    • SMAUG
    • Smaug 1
    • Smaug homolog
    • SMAUG, Drosophila, homolog of, 1
    • SMAUG1
    • SMG
    • SMGA
    • Sterile alpha motif domain containing 4A
    • Sterile alpha motif domain containing protein 4A
    see all
  • Relevance

    Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).
  • Cellular localization

    Cytoplasm. Cell projection, dendrite. Cell junction, synapse, synaptosome. Enriched in synaptoneurosomes (By similarity). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1.

Images

  • ab161511 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161511 has not yet been referenced specifically in any publications.

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