Recombinant Human SEC14 like protein 2 (ab161678)

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SDS-PAGE - Recombinant Human SEC14 like protein 2 (ab161678)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human SEC14 like protein 2

    • Expression system

      Wheat germ

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        DIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETIT IIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFP

      • Amino acids

        101 to 199

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab161678 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • Alpha tocopherol associated protein
      • Alpha-tocopherol-associated protein
      • C22orf6
      • hTAP
      • KIAA1186
      • KIAA1658
      • MGC65053
      • OTTHUMP00000198972
      • OTTHUMP00000198973
      • OTTHUMP00000198974
      • OTTHUMP00000199021
      • S14L2_HUMAN
      • SEC14 (S. cerevisiae) like 2
      • SEC14 like 2 (S. cerevisiae)
      • SEC14 like protein 2
      • SEC14-like protein 2
      • Sec14l2
      • SPF
      • Squalene transfer protein
      • Supernatant protein factor
      • TAP
      • TAP1
      • tocopherol-associated protein
      see all

    • Function

      Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.

    • Tissue specificity

      Widely expressed. Strong expression in liver, brain and prostate.

    • Sequence similarities

      Contains 1 CRAL-TRIO domain.
      Contains 1 GOLD domain.

    • Developmental stage

      Low expression in fetal tissues.

    • Cellular localization

      Cytoplasm. Nucleus. Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human SEC14 like protein 2 (ab161678)
      SDS-PAGE - Recombinant Human SEC14 like protein 2 (ab161678)
      ab161678 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab161678? Please let us know so that we can cite the reference in this datasheet.

    ab161678 has not yet been referenced specifically in any publications.

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