Recombinant Human SEC14 like protein 2 (ab161678)

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Overview

Description

  • Nature

    Recombinant

  • Source

    Wheat germ
  • Amino Acid Sequence

    • Species

      Human

    • Sequence

      DIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETIT IIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFP

    • Amino acids

      101 to 199

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161678 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Alpha tocopherol associated protein
    • Alpha-tocopherol-associated protein
    • C22orf6
    • hTAP
    • KIAA1186
    • KIAA1658
    • MGC65053
    • OTTHUMP00000198972
    • OTTHUMP00000198973
    • OTTHUMP00000198974
    • OTTHUMP00000199021
    • S14L2_HUMAN
    • SEC14 (S. cerevisiae) like 2
    • SEC14 like 2 (S. cerevisiae)
    • SEC14 like protein 2
    • SEC14-like protein 2
    • Sec14l2
    • SPF
    • Squalene transfer protein
    • Supernatant protein factor
    • TAP
    • TAP1
    • tocopherol-associated protein
    see all

  • Function

    Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.

  • Tissue specificity

    Widely expressed. Strong expression in liver, brain and prostate.

  • Sequence similarities

    Contains 1 CRAL-TRIO domain.
    Contains 1 GOLD domain.

  • Developmental stage

    Low expression in fetal tissues.

  • Cellular localization

    Cytoplasm. Nucleus. Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human SEC14 like protein 2 (ab161678)
    SDS-PAGE - Recombinant Human SEC14 like protein 2 (ab161678)
    ab161678 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161678 has not yet been referenced specifically in any publications.

Publishing research using ab161678? Please let us know so that we can cite the reference in this datasheet.

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