Overview

  • Product name

    Recombinant Human SEC31B protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDF RDPSLDLKHRGVLSALSRFHKLVWGSFGSGLLESSGVIAGGGDNGMLILY NVTHILSSGKEPVIAQKQKHTGAVRALDFNPFQGNLLASGASDSEIFIWD LNNLNVPMTLGSKSQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKN EPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASS PLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKLPT QSSWCFDVQWCPRDPSVFSAASFNGWISLYAVMGRSWEVQHMRQADKV
    • Amino acids

      1 to 348
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • SEC31L2
    • Gm341
    • Protein transport protein Sec31B
    • SC31B_HUMAN
    • SEC31 B
    • SEC31 homolog B
    • SEC31 homolog B (S. cerevisiae)
    • SEC31 like 2
    • SEC31 related protein B
    • SEC31-like protein 2
    • SEC31-related protein B
    • SEC31B
    • SEC31B 1
    • SEC31B-1
    • Secretory pathway component Sec31B 1
    • secretory pathway component Sec31B1
    see all
  • Function

    As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.
  • Tissue specificity

    Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level).
  • Sequence similarities

    Belongs to the WD repeat SEC31 family.
    Contains 8 WD repeats.
  • Post-translational
    modifications

    Monoubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex, leading to regulate the size of COPII coats.
  • Cellular localization

    Cytoplasm. Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum membrane.
  • Information by UniProt

Images

  • ab161845 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161845 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab161845.
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