Overview

  • Product name

    Recombinant Human SEI-1 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSHMLSKGL KRKREEEEEK EPLAVDSWWL DPGHTAVAQA PPAVASSSLF DLSVLKLHHS LQQSEPDLRH LVLVVNTLRR IQASMAPAAA LPPVPSPPAA PSVADNLLAS SDAALSASMA SLLEDLSHIE GLSQAPQPLA DEGPPGRSIG GAAPSLGALD LLGPATGCLL DDGLEGLFED IDTSMYDNEL WAPASEGLKP GPEDGPGKEE APELDEAELD YLMDVLVGTQ ALERPPGPGR
    • Molecular weight

      27 kDa including tags
    • Amino acids

      1 to 236
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab130022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 85 % SDS-PAGE.
    ab130022 was purified using conventional chromatography.
  • Form

    Liquid
  • Additional notes

    Previously labelled as Sertad1.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • CDK4 binding protein p34SEI
    • CDK4 binding protein p34SEI1
    • CDK4-binding protein p34SEI1
    • SEI-1
    • SEI1
    • SERTA domain containing 1
    • SERTA domain-containing protein 1
    • SERTAD1
    • SRTD1_HUMAN
    • Transcriptional regulator interacting with the PHD-bromodomain 1
    • TRIP Br1
    • TRIP-Br1
    see all
  • Function

    Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).
  • Sequence similarities

    Contains 1 SERTA domain.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3 µg ab130022.

References

ab130022 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab130022.
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