Description

  • Product name

    Recombinant Human SEMA6D protein
  • Expression system

    Wheat germ
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      KLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQ MAHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNS
    • Amino acids

      852 to 940
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • KIAA1479
    • Q8NFY4
    • Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
    • Semaphorin 6D
  • Relevance

    SEMA6D belongs to the semaphorin family of proteins, which are a large family of secreted and transmembrane proteins, some of which function as repellent signals during axon guidance. SEMA6D shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro and may be a stop signal for DRG neurons in their target areas, and possibly also for other neurons. It may also be involved in the maintenance and remodeling of neuronal connections.
  • Cellular localization

    Isoforms 1-6: Cell membrane; Single-pass type I membrane protein. Isoform 7: Cytoplasm.

Images

  • ab164191 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164191 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab164191.
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