Description

  • Product name

    Recombinant Human SENP1 protein (Catalytic domain)
    See all SENP1 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      EF PEITEEMEKE IKNVFRNGNQ DEVLSEAFRL TITRKDIQTL NHLNWLNDEI INFYMNMLME RSKEKGLPSV HAFNTFFFTK LKTAGYQAVK RWTKKVDVFS VDILLVPIHL GVHWCLAVVD FRKKNITYYD SMGGINNEAC RILLQYLKQE SIDKKRKEFD TNGWQLFSKK SQEIPQQMNG SDCGMFACKY ADCITKDRPI NFTQQHMPYF RKRMVWEILH RKLL
    • Predicted molecular weight

      27 kDa
    • Amino acids

      419 to 644
    • Additional sequence information

      NM_001267594.1

Specifications

Our Abpromise guarantee covers the use of ab206002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Constituents: 0.24% Tris, 0.87% Sodium chloride, 0.02% Beta mercaptoethanol, 10% Glycerol

General Info

  • Alternative names

    • SENP 1
    • SENP1
    • SENP1_HUMAN
    • Sentrin specific protease 1
    • Sentrin-specific protease 1
    • Sentrin/SUMO specific protease
    • Sentrin/SUMO specific protease 1
    • Sentrin/SUMO specific protease SENP 1
    • Sentrin/SUMO specific protease SENP1
    • Sentrin/SUMO-specific protease SENP1
    • SUMO1/sentrin specific peptidase 1
    • SUMO1/sentrin specific protease 1
    • SuPr 2
    • SuPr2
    see all
  • Function

    Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.
  • Tissue specificity

    Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
  • Sequence similarities

    Belongs to the peptidase C48 family.
  • Cellular localization

    Nucleus. Cytoplasm. Shuttles between cytoplasm and nucleus.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab206002 (5µg) Coomassie-stained. 

References

ab206002 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab206002.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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