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Epigenetics and Nuclear Signaling Ubiquitin & Ubiquitin Like Modifiers E2 Ubiquitin Conjugating Enzymes
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Recombinant Human SFT protein (ab139633)

  • Datasheet
  • SDS
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SDS-PAGE - Recombinant Human SFT protein (ab139633)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: >= 95% Densitometry
    • Tags: His tag N-Terminus
    • Suitable for: WB, SDS-PAGE

    Description

    • Product name

      Recombinant Human SFT protein
      See all SFT proteins and peptides
    • Purity

      >= 95 % Densitometry.

    • Expression system

      Escherichia coli
    • Accession

      P51668
    • Protein length

      Full length protein
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        MALKRIQKEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV PDIAQIYKSD KEKYNRHARE WTQKYAM
      • Predicted molecular weight

        17 kDa including tags
      • Amino acids

        1 to 147
      • Tags

        His tag N-Terminus

    Associated products

    • Related Products

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)

    Specifications

    Our Abpromise guarantee covers the use of ab139633 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 7.00
      Preservative: 1.02% Imidazole
      Constituents: 0.002% PMSF, 0.7% Sodium phosphate, 0.004% DTT, 25% Glycerol, 1.74% Sodium chloride

    General Info

    • Alternative names

      • E2(17)KB1
      • SFT
      • Stimulator of Fe transport
      • UB2D1_HUMAN
      • UBC 4/5
      • UBC4/5
      • UBC4/5 homolog
      • UBC4/5, S. cerevisiae, homolog of
      • UBCH 5
      • UBCH 5A
      • UbcH5
      • UBCH5A
      • Ube2d1
      • Ubiquitin carrier protein
      • Ubiquitin carrier protein D1
      • Ubiquitin conjugating enzyme E2 17 kDa 1
      • Ubiquitin conjugating enzyme E2 D1
      • Ubiquitin conjugating enzyme E2D 1
      • Ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog yeast)
      • Ubiquitin conjugating enzyme UBCH5A
      • Ubiquitin protein ligase D1
      • Ubiquitin-conjugating enzyme E2 D1
      • Ubiquitin-conjugating enzyme E2(17)KB 1
      • Ubiquitin-conjugating enzyme E2-17 kDa 1
      • Ubiquitin-protein ligase D1
      see all
    • Function

      Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
    • Tissue specificity

      Ubiquitous. Up-regulated in livers of iron-overloaded patients with hereditary hemochromatosis.
    • Pathway

      Protein modification; protein ubiquitination.
    • Sequence similarities

      Belongs to the ubiquitin-conjugating enzyme family.
    • Cellular localization

      Cytoplasm.
    • Target information above from: UniProt accession P51668 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human SFT protein (ab139633)
      SDS-PAGE - Recombinant Human SFT protein (ab139633)
      SDS PAGE analysis of ab139633

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab139633? Please let us know so that we can cite the reference in this datasheet.

    ab139633 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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