Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 90% SDS-PAGE
- Active: Yes
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE, Functional Studies
Product nameRecombinant human SGPL1 protein (Active)
Purity>= 90 % SDS-PAGE.
Expression systemBaculovirus infected Sf9 cells
Protein lengthProtein fragment
Predicted molecular weight58 kDa
Amino acids59 to 785
TagsHis tag C-Terminus
Our Abpromise guarantee covers the use of ab271748 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
Preservative: 1.7% Imidazole
Constituents: 0.79% Tris HCl, 2.9% Sodium chloride, Methionine, PLP, 0.03% TCEP, 10% Glycerol (glycerin, glycerine)
This product is an active protein and may elicit a biological response in vivo, handle with caution.
FunctionCleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.
Tissue specificityFound in liver and kidney.
PathwayLipid metabolism; sphingolipid metabolism.
Sequence similaritiesBelongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
Cellular localizationEndoplasmic reticulum membrane.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab271748 has not yet been referenced specifically in any publications.