Recombinant Human Skp1 protein (ab90687)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Suitable for: SDS-PAGE, WB
Description
-
Product name
Recombinant Human Skp1 protein -
Purity
> 90 % SDS-PAGE.
ab90687 is purified using conventional chromatography techniques. -
Expression system
Escherichia coli -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Human
-
Associated products
-
Related Products
Specifications
Our Abpromise guarantee covers the use of ab90687 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
SDS-PAGE
Western blot
-
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.29% Sodium chloride
General Info
-
Alternative names
- Cyclin A/CDK2 associated p19
- Cyclin A/CDK2 associated protein p19
- Cyclin-A/CDK2-associated protein p19
see all -
Function
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110. -
Pathway
Protein modification; protein ubiquitination. -
Sequence similarities
Belongs to the SKP1 family. - Information by UniProt
Images
-
15% SDS-PAGE showing ab90687 (3µg).
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab90687 has not yet been referenced specifically in any publications.