The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
BA CoA ligase
Bile acid CoA ligase
Bile acid-CoA ligase
Bile acyl CoA synthetase
Bile acyl-CoA synthetase
Cholate CoA ligase
Fatty acid Coenzyme A ligase very long chain 3
Fatty acid transport protein 5
Fatty-acid-coenzyme A ligase
Solute carrier family 27 (fatty acid transporter) member 5
Solute carrier family 27 member 5
Very long chain acyl CoA synthetase homolog 2
Very long chain acyl CoA synthetase related protein
very long-chain 3
Very long-chain acyl-CoA synthetase homolog 2
Very long-chain acyl-CoA synthetase-related protein
Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.
Predominantly expressed in liver.
Belongs to the ATP-dependent AMP-binding enzyme family.