Description

  • Product name

    Recombinant Human SLURP1 protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MASRWAVQLLLVAAWSMGCGEALKCYTCKEPMTSASCRTITRCKPEDTAC MTTLVTVEAEYPFNQSPVVTRSCSSSCVATDPDSIGAAHLIFCCFRDLCN SEL
    • Amino acids

      1 to 103
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab163504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Anti neoplastic urinary protein
    • ANUP
    • ARS
    • ARS component B
    • ARS(component B) 81/S
    • ArsB
    • LY6LS
    • Lymphocyte antigen 6 like secreted
    • MDM
    • Results in cobblestone changes in the skin of the palm
    • Secreted Ly 6/uPAR related protein 1
    • Secreted LY6/PLAUR domain containing 1
    • Secreted Ly6/uPAR related protein 1
    • SLURP 1
    see all
  • Relevance

    SLURP1 (Secreted LY6/PLAUR domain containing 1) belongs to the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. SLURP1 potentiates alpha-7 nicotinic acetylcholine receptors (CHRNA7) in keratinocytes and is implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. It is a marker of late differentiation of the skin and has an antitumor activity. Mutations in the SLURP1 gene are the cause of Mal de Meleda (MDM), a rare autosomal recessive genetic disease, characterized by inflammatory palmoplantar keratoderma.
  • Cellular localization

    Secreted

Images

  • ab163504 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab163504 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab163504.
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