Recombinant Human SMC5 protein (ab161544)
- Datasheet
- References
- Protocols
Overview
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Product nameRecombinant Human SMC5 protein
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Protein lengthProtein fragment
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTA CKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNTWNLKAFQRR RRRITFTQPS
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Amino acids992 to 1101
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab161544 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- hSMC 5
- hSMC5
- KIAA0594
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RelevanceStructural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromosome proteins are conserved in eukaryotes lead to mitotic chromosome segregation defects, suggesting a critical function of SMC family proteins in mitotic chromosome dynamics.
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Cellular localizationNucleus. Chromosome. Chromosome; telomere. Note: Associates with chromatin. Localizes to PML nuclear bodies in ALT cell lines.
Images
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SDS-PAGE - Recombinant Human SMC5 protein (ab161544)ab161544 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab161544 has not yet been referenced specifically in any publications.
