Key features and details
- Expression system: Wheat germ
- Suitable for: ELISA, SDS-PAGE, WB
Product nameRecombinant Human Smoothened protein
See all Smoothened proteins and peptides
Expression systemWheat germ
Protein lengthProtein fragment
SequenceNLWLVEAEISPELQKRLGRKKKRRKRKKEVCPLAPPPELHPPAPAPSTIP RLPQLPRQKCLVAAGAWGAGDSCRQ GAWTLVSNPFCPEPSPPQDPFLP SAPAPVAWAHGRRQGLGPIHSRTNLMDTELMDADSDF
Predicted molecular weight40 kDa including tags
Amino acids653 to 787
Our Abpromise guarantee covers the use of ab114221 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.3% Glutathione, 0.79% Tris HCl
- Frizzled family member 11
FunctionG protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
Sequence similaritiesBelongs to the G-protein coupled receptor Fz/Smo family.
Contains 1 FZ (frizzled) domain.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab114221 has not yet been referenced specifically in any publications.