Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERR RDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYM ESEGGDGYLAPENGYLMEAAPE
    • Molecular weight

      39 kDa including tags
    • Amino acids

      316 to 437

Specifications

Our Abpromise guarantee covers the use of ab132548 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 µg/µl.

     This product was previously labelled as SNRP70

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • RNPU1Z
    • Rnulp70
    • RPU1
    • Small nuclear ribonucleoprotein 70 (U1)
    • Small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen)
    • Small nuclear ribonucleoprotein 70kDa (U1)
    • Small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)
    • snRNP70
    • Snrp 70
    • SNRP70
    • U1 70K
    • U1 small nuclear ribonucleoprotein 70 kDa
    • U1 small nuclear ribonucleoprotein polypeptide A
    • U1 snRNP 70 kDa
    • U170K
    • U1AP
    • U1AP1
    • U1RNP
    see all
  • Relevance

    SNRP70 is an RNA-binding protein that is a specific component of the U1 small nuclear ribonucleoprotein complex and constitutes the major anti-(U1) RNP autoimmune antigen. SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA.
  • Cellular localization

    Nuclear

Images

  • 12.5% SDS-PAGE Stained with Coomassie Blue.

References

ab132548 has not yet been referenced specifically in any publications.

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