Description

  • Product name

    Recombinant Human SNX16 protein
  • Expression system

    Wheat germ
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMG NFKQTSVPDQMDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPET VNWEDRPSTPTILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSR LNDKLKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKD IANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRLQKELLEKQKE MESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED
    • Predicted molecular weight

      64 kDa including tags
    • Amino acids

      1 to 344

Associated products

Specifications

Our Abpromise guarantee covers the use of ab131945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 µg/µl.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • DKFZp666H147
    • OTTHUMP00000227313
    • OTTHUMP00000227314
    • SNX16
    • SNX16_HUMAN
    • Sorting nexin-16
    see all
  • Function

    May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
  • Tissue specificity

    Detected in placenta, lung, liver,heart and pancreas.
  • Sequence similarities

    Belongs to the sorting nexin family.
    Contains 1 PX (phox homology) domain.
  • Domain

    The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.
  • Cellular localization

    Early endosome membrane. Late endosome membrane. Cytoplasm. Lysosome.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab131945 at approximately 63.58 kDa.
    Stained with Coomassie Blue.

References

ab131945 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab131945.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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