Recombinant Human Snx6 protein (ab163697)
- Datasheet
- References
- Protocols
Description
-
Product name
Recombinant Human Snx6 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
MTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILGRDLNFHVF LEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTF LLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKF FLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRS LVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFK TRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT -
Amino acids
1 to 290 -
Tags
GST tag N-Terminus
-
Specifications
Our Abpromise guarantee covers the use of ab163697 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Western blot
ELISA
-
Form
Liquid -
Additional notes
Protein concentration is above or equal to 0.05 mg/ml. -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
-
Alternative names
- Sorting Nexin 6
- TFAF2
- TRAF4 Associated Factor 2
-
Relevance
Snx6 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. -
Cellular localization
Endosomes
Images
-
SDS-PAGE - Recombinant Human Snx6 protein (ab163697)ab163697 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab163697 has not yet been referenced specifically in any publications.
